Yeeran

Yeeran takes the lead in launching the first portable small animal ultrasound equipment. It is a high-frequency and high-resolution small animal ultrasound imaging system developed for experimental small animals, providing researchers with non-invasive continuous analysis, high-resolution image quality and quantitative analysis of tissue structure and blood flow velocity.

Application Examples 

Cardiac

Mouse heart tissue Doppler

Short axis M-type

Long axis M-type

Strain Function

Apical four-chamber section

Angiography

mouse pulmonary artery

mouse abdominal aorta

Mouse carotid artery

Aortic arch blood flow

Brain

mouse brain

 

developmental biology

Cardiac Function Evaluation of 15-day-old Fetal mouse

Cerebral blood flow images of fetal mouse

Umbilical Artery Spectrum

Uterine Imaging

Uterine Imaging

lmaging Station

Publications Library

1.α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure
Cell Res. 2023 Sep;33(9):679-698.
doi: 10.1038/s41422-023-00844-w. Epub 2023 Jul 13.  

2.BAF155 promotes cardiac hypertrophy and fibrosis through inhibition of WWP2-mediated PARP1 ubiquitination
Cell Discov. 2023 May 8;9(1):46.
doi: 10.1038/s41421-023-00555-x.

3.Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo 
Mil Med Res. 2022 Feb 14;9(1):9.
doi: 10.1186/s40779-022-00369-0.

4.Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles 
Nat Biomed Eng. 2020 Nov;4(11):1063-1075.
doi: 10.1038/s41551-020-00637-1. Epub 2020 Nov 6.

5.Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment
Bioact Mater. 2022 Dec 6:23:526-538.
doi: 10.1016/j.bioactmat.2022.11.015. eCollection 2023 May.

6.Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence
Nat Commun. 2023 Mar 10;14(1):1323.
doi: 10.1038/s41467-023-37094-8.

7.Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution
Bioact Mater. 2021 Aug 27:9:183-197.
doi: 10.1016/j.bioactmat.2021.08.008. eCollection 2022 Mar.

8.Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment
Bioact Mater. 2022 Dec 6:23:526-538.
doi: 10.1016/j.bioactmat.2022.11.015. eCollection 2023 May.

9.Upconversion nanoparticles regulated drug & gas dual-effective nanoplatform for the targeting cooperated therapy of thrombus and anticoagulation
Bioact Mater. 2022 Mar 17:18:91-103.
doi: 10.1016/j.bioactmat.2022.03.013. eCollection 2022 Dec.

10.V1-Cal hydrogelation enhances its effects on ventricular remodeling reduction and cardiac function improvement post myocardial infarction
Chem Eng J. 2022 Apr 1;433(Pt 1):134450.
doi: 10.1016/j.cej.2021.134450. Epub 2022 Jan 4.

11.1-Deoxynojirimycin promotes cardiac function and rescues mitochondrial cristae in mitochondrial hypertrophic cardiomyopathy
J Clin Invest. 2023 Jul 17;133(14):e164660.
doi: 10.1172/JCI164660.

12.Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries
Acta Pharm Sin B. 2023 Jun;13(6):2369-2382.
doi: 10.1016/j.apsb.2022.12.002. Epub 2022 Dec 8.